The Loneliest Road, often known as U.S. Route 50, spans the whole United States from coast to coast. Your journey will take you from Sacramento, California to Ocean City, Maryland, a distance of over 3,200 miles. This highway, which passes through small villages and wide open areas, was dubbed "The Loneliest Road in America" by Life magazine in 1986 and offers a glimpse of what some regard to be the "true America."